86800-30-8Relevant academic research and scientific papers
Pyridazinone derivatives
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, (2008/06/13)
This invention relates to pyridazinone derivatives of the general formula: STR1 [wherein R1 stands for a hydrogen atom or a lower alkyl group; R2 for a hydrogen atom or a lower alkyl group; and A for (i) a ring selected from a benzene ring, a furan ring, a thiophene ring and a pyridine ring (on which ring 1-3 substituents or atoms selected from amino groups, nitro groups, lower alkanoylamino groups, hydroxyl groups, lower alkanoyloxy groups, sulfamoyl groups and halogen atoms may be present), or (ii) a grouping of the formula: STR2 (wherein R3 stands for a hydrogen atom, a lower alkyl group, a phenyl(lower)alkyl, a hydroxyphenyl(lower)alkyl group, a lower alkylmercapto(lower)alkyl group, a benzylmercapto(lower)alkyl group, a guanidino(lower)alkyl group, a nitroguanidino(lower)alkyl group, an indolyl(lower)alkyl group, a carbamoyl(lower)alkyl group or a carboxy(lower)alkyl group, R4 for a hydrogen atom or a lower alkyl group, R5 for a hydrogen atom, a lower alkyl group, a lower alkanoyl group, a benzoyl or a benzyloxycarbonyl group, and R3 and R4 may be combined to form a grouping of the formula: STR3 which forms a ring), or (iii) a grouping of the formula: STR4 (wherein R6, R7 and R8 each stand for a hydrogen atom or a lower alkyl group, B is an oxygen atom or a sulfur atom, R9 stands for a hydrogen atom or a lower alkanoyl group, and n is 0 or 1)].
