868125-35-3

Upstream product

• 868049-77-8 benzyl [2-(4-ethoxy-phenyl)-1,1-dimethyl-ethyl]-carbamate 

Downstream Products

• 868049-79-0 2-(4-ethoxy-phenyl)-1,1-dimethyl-ethylamine hydrochloride 
• 868125-36-4 6-benzyloxy-8-{2-[2-(4-ethoxy-phenyl)-1,1-dimethyl-ethylamino]-1-hydroxy-ethyl}-4H-benzo[1,4]oxazin-3-one 

Relevant academic research and scientific papers

Discovery of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24 h bronchodilatory efficacy

Compound 4p was identified from a series of 6-hydroxy-4H-benzo[1,4]oxazin-3-ones as potent agonist of the human β2-adrenoceptor with a high β1/β2-selectivity. A complete reversal of acetylcholine-induced bronchoconstrictio

Novel medicaments for the treatment of respiratory diseases

The present invention relates to the use of the compounds of general formula 1 wherein the groups R1, R2 and R3 may have the meanings given in the claims and in the specification, for preparing a pharmaceutical composition

Aerosol formulation for the inhalation of beta-agonists

The present invention relates to a propellant-free aerosol formulation which [contains] one or more compounds of general formula 1 wherein the groups R1, R2, R3 and X? may have the meanings given in the claims a

Novel medicament combinations for the treatment of respiratory diseases

The present invention relates to new medicament combinations which contain in addition to one or more, preferably one, compound of general formula 1 wherein the groups R1, R2 and R3 may have the meanings given in the claim