868151-77-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 94820-26-5 (2S,3R)-2-(benzyloxycarbonylamino)-3-tertiary-butyldimethylsilyloxybutanoic acid 
• 19728-63-3 N-benzyloxycarbonyl-L-treonine 
• 74-88-4 methyl iodide 
• 352636-79-4 (S)-4-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 868151-87-5 (S)-1-[(2S,3S)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-hydroxy-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-88-6 (S)-1-[(2S,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-hydroxy-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-89-7 (S)-1-[(2R,3S)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-hydroxy-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-86-4 (S)-1-[(2R,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-hydroxy-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-83-1 (S)-1-[(2S,3S)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-84-2 (S)-1-[(2S,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-85-3 (S)-1-[(2R,3S)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 
• 868151-82-0 (S)-1-[(2R,3R)-2-[(2S,3R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-(4-benzyloxy-phenyl)-3-methoxy-propionyl]-piperidine-2-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of tripeptide hydrolysate from papuamide A: Determination of absolute stereostructure of β-methoxytyrosine

Four diastereomers, (2R, 3R), (2S, 3S), (2S, 3R) and (2R, 3S) at β-methoxytyrosine (β-OMeTyr), of the tripeptide hydrolysate, H-(S)-N-MeThr-β-OMeTyr-(S)-Hpr-OH, from papuamide A have been synthesized. Comparison of the 1H NMR data of the natura

Synthesis of N-protected N-methyl serine and threonine

Two efficient and convenient syntheses of N-Cbz and N-Fmoc N-methyl serine and threonine are described. The amino acid side-chain alcohol can be protected as a TBDMS ether in very good yield or left free, followed by the formation and subsequent reduction of the corresponding oxazolidinone.