868166-10-3Relevant academic research and scientific papers
Design of a novel class of biphenyl CETP inhibitors
Lu, Zhijian,Napolitano, Joann B.,Theberge, Ashleigh,Ali, Amjad,Hammond, Milton L.,Tan, Eugene,Tong, Xinchun,Xu, Suoyu S.,Latham, Melanie J.,Peterson, Laurence B.,Anderson, Matt S.,Eveland, Suzanne S.,Guo, Qiu,Hyland, Sheryl A.,Milot, Denise P.,Chen, Ying,Sparrow, Carl P.,Wright, Samuel D.,Sinclair, Peter J.
scheme or table, p. 7469 - 7472 (2011/01/12)
A new class of CETP inhibitors was designed and prepared. These compounds are potent both in vitro and in vivo. The most active compound (12d) has shown an ability to raise HDL significantly in transgenic mouse PD model.
CETP INHIBITORS
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Page/Page column 46, (2010/02/14)
Compounds of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formu
