86817-85-8Relevant academic research and scientific papers
Palladium-catalysed Spirocyclisation of 3-Acetoxy-1-(4-aminoalkyl)cyclohexenes. Synthesis of (+/-)-Depentylperhydrohistrionicotoxin
Carruthers, William,Cumming, S. Andrew
, p. 360 - 361 (2007/10/02)
Palladium(0)-catalysed cyclisation of 3-acetoxy-1-(4-aminoalkyl)cyclohexenes provides easy access to the 1-azaspiroundecane ring system found in the histrionicotoxins; this has been exploited in a synthesis of (+/-)-depentylperhydrohistrionicotoxin.
PALLADIUM ASSISTED SYNTHESIS OF 1-AZASPIROCYCLES
Godleski, Stephen A.,Meinhart, James D.,Miller, David J.,Wallendael, Shawn Van
, p. 2247 - 2250 (2007/10/02)
A facile, general route to 1-azaspirocycles utilizing a ?-allyl palladium complex in the key cyclization step has been developed.
