86818-82-8

Upstream product

• 13450-77-6 4-chlorohippuric acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 86818-94-2 2-(4-Chloro-phenyl)-5-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-3-(4-morpholin-4-yl-phenyl)-3,5-dihydro-imidazol-4-one 
• 86818-84-0 α-(p-Chlorophenylcarboxamido)-β-(3,4-dimethoxyphenyl)acrylic acid p-morpholinophenylcarboxamide 

Relevant academic research and scientific papers

Synthesis of 2-Aryl-1-(4-morpholinophenyl)-4-(3,4-disubstituted-benzylidene)imidazolin-5-ones as CNS Active Agents

The title compounds (IVa-l) have been prepared by the action of p-morpholinoaniline (II) on appropriate oxazolin-5-ones (III) in the presence of anhyd.ZnCl2 or super dry pyridine.However, the interaction of II and III in ordinary pyridine/benzene or in the absence of anhydr.ZnCl2 gives p-morpholinophenylcarboxamides (V) of α-arylcarboxamido-β-(3,4-disubstituted phenyl)acrylic acids indicating the reaction of II and III to be moisture sensitive.Compounds IV have been found to be nontoxic and psychotropic.