868249-02-9Relevant academic research and scientific papers
Preparation and structural, biochemical, and pharmaceutical characterizations of bile acid-modified long-acting exendin-4 derivatives
Son, Sohee,Su, Young Chae,Chang, Wan Kim,Yang, Gyu Choi,Sung, Youb Jung,Lee, Seulki,Kang, Choon Lee
, p. 6889 - 6896 (2009)
To develop an effective long-acting antidiabetic, the GLP-1 analogue of exendin-4 was modified with three different bile acids (BAs; cholic, deoxycholic, or lithocholic acid), at its two lysine residues. The biological, pharmaceutical, and physicochemical
