Welcome to LookChem.com Sign In|Join Free

CAS

  • or
METHYL N-CBZ-3-PIPERIDINEACETATE, also known as carbamic acid, [(1R)-1-(benzyloxycarbonyl)-3-methylbutyl]-, methyl ester, is an organic compound that serves as an intermediate in the pharmaceutical industry. It is utilized in the synthesis of various drugs due to its ability to elicit biological responses. Depending on its stereochemistry, this chemical can be involved in both the organic synthesis of active pharmaceutical ingredients (APIs) and research and development processes within the pharmaceutical sector. However, it is essential to handle this compound with appropriate safety measures to prevent potential hazards.

86827-08-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 86827-08-9 Structure
  • Basic information

    1. Product Name: METHYL N-CBZ-3-PIPERIDINEACETATE
    2. Synonyms: N-CBZ-3-PIPERIDINEACETIC ACID METHYL ESTER;METHYL N-CBZ-3-PIPERIDINEACETATE;1-N-Cbz-3-Methoxycarbonylmethyl-piperidine;1-Cbz-3-Piperidineacetic Acid Methyl Ester;Methyl 3-(N-Cbz-piperidinoxy)acetate;Methyl N-Cbz-3-piperidylacetate;Benzyl 3-(2-Methoxy-2-oxoethyl)piperidine-1-carboxylate;Benzyl 3-(2-methoxy-2-oxoethyl)
    3. CAS NO:86827-08-9
    4. Molecular Formula: C16H21NO4
    5. Molecular Weight: 291.34
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 86827-08-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 402.9 °C at 760 mmHg
    3. Flash Point: 197.5 °C
    4. Appearance: /
    5. Density: 1.149g/cm3
    6. Vapor Pressure: 1.06E-06mmHg at 25°C
    7. Refractive Index: 1.526
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: METHYL N-CBZ-3-PIPERIDINEACETATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: METHYL N-CBZ-3-PIPERIDINEACETATE(86827-08-9)
    12. EPA Substance Registry System: METHYL N-CBZ-3-PIPERIDINEACETATE(86827-08-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 86827-08-9(Hazardous Substances Data)

86827-08-9 Usage

Uses

Used in Pharmaceutical Industry:
METHYL N-CBZ-3-PIPERIDINEACETATE is used as an intermediate compound in the synthesis of various drugs for its ability to elicit biological responses. It plays a crucial role in the development of new pharmaceuticals and the improvement of existing ones.
Used in Organic Synthesis of Active Pharmaceutical Ingredients (APIs):
METHYL N-CBZ-3-PIPERIDINEACETATE is used as a key component in the organic synthesis of APIs, contributing to the creation of effective and safe medications.
Used in Research and Development Processes:
In the pharmaceutical industry, METHYL N-CBZ-3-PIPERIDINEACETATE is employed in research and development processes to explore its potential applications and optimize its use in drug synthesis. This helps in advancing the understanding of its properties and enhancing its role in pharmaceutical formulations.

Check Digit Verification of cas no

The CAS Registry Mumber 86827-08-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,8,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 86827-08:
(7*8)+(6*6)+(5*8)+(4*2)+(3*7)+(2*0)+(1*8)=169
169 % 10 = 9
So 86827-08-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H21NO4/c1-20-15(18)10-14-8-5-9-17(11-14)16(19)21-12-13-6-3-2-4-7-13/h2-4,6-7,14H,5,8-12H2,1H3

86827-08-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name benzyl 3-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names N-Cbz-3-piperidineacetic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86827-08-9 SDS

86827-08-9Downstream Products

86827-08-9Relevant articles and documents

Fragment-oriented synthesis: β-elaboration of cyclic amine fragments using enecarbamates as platform intermediates

Trindade, Alexandre F.,Faulkner, Emily L.,Leach, Andrew G.,Nelson, Adam,Marsden, Stephen P.

supporting information, p. 8802 - 8805 (2020/08/17)

A strategy for the β-sp3 functionalisation of cyclic amines is described. Regioselective conversion of protected amines to enecarbamates is achieved through electrochemical oxidation; these intermediates can be derivatised by functionalised alkyl halides under photoredox catalysis. The potential of the methods is highlighted by direct growth of a DCP2B-binding fragment. This journal is

Radical cyclization reactions of α-silyl amine α,β-unsaturated ketone and ester systems promoted by single electron transfer photosensitization

Jeon, Yoon T.,Lee, Chao-Pin,Mariano, Patrick S.

, p. 8847 - 8863 (2007/10/02)

The results of a broad investigation of the preparative and mechanistic aspects of single electron transfer (SET) promoted photocyclization reactions of α-silyl amino and amido α,β-unsaturated esters and ketones are presented. A number of unique and synthetically useful features of these processes, driven by α-silyl amine and amide cation radical desilylation and by intramolecular conjugate addition of intermediate α-amino and α-amido carbon-centered radicals to unsaturated esters and ketones, are described. Comparisons of the SET-sensitized and direct irradiation promoted reactions of these systems have shown how the former method is superior in inducing photocyclization reactions in cases where the α,β-unsaturated ketone or ester excited states are too reactive to be quenched by SET from the tethered amine donors and where diradicals produced as intermediates in the direct-irradiation reactions undergo fragmentation rather than cyclization. The current efforts have also demonstrated that problems associated with the ready oxidation of intermediate α-amino radicals can be avoided by the proper selection of photosensitizer or amine N substituents. Lastly, the synthetic versatility of this chemistry, exemplified by its application to the preparation of a number of N-heterocyclic substances by pathways involving either exo or endo radical cyclization, is presented.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 86827-08-9