868272-97-3Relevant academic research and scientific papers
Reactions of aminophosphines and aminobis(phosphines) with aldehydes and ketones: Coordination complexes of the resultant aminobis(alkylphosphineoxides) with cobalt, uranium, thorium and gadolinium salts: Crystal and molecular structures of Ph2P(O)CH(C6H4OH-o)N(H)Ph, Ph2P(O)CH(OH)C6H4OH-o and Ph 2P(O)N(H)Ph
Priya, Srinivasan,Balakrishna, Maravanji S.,Mobin, Shaikh M.
, p. 1641 - 1650 (2005)
The reaction of aminophosphines and aminobis(phosphines) with aldehydes leads to either insertion of carbon fragments into the P(III)-N bonds or formation of α-hydroxyphosphine oxides through P(III)-N bond cleavage. Reaction of 1,2-C6H4{N(H)PPh2}2 with paraformaldehyde gives the P(III)-N bond inserted product 1,2-C 6H4{N(H)CH2P(O)Ph2}2, whereas 1,3-C6H4{N(H)PPh2}2 forms an analogous product but with an additional methylene group inserted between the two nitrogen centers through nucleophilic addition to form a bicyclic derivative, 1,3-C6H4{Ph2P(O)CH 2N(μ-CH2)NCH2P(O)Ph2}. Reactions of Ph2PN(H)Ph with aromatic aldehydes, RCHO (R = C6H 4OH-o, 5-BrC6H3OH-o, (η5-C 5H5)Fe(η5-C5H4-)) lead to the insertion of 'RCH' into the P(III)-N bond to give Ph 2P(O)CH(R)N(H)Ph. The reactions of aminobis(phosphine), Ph 2PN(nBu)PPh2 with both aromatic and aliphatic aldehydes lead to the formation of α-hydroxy phosphine oxide derivatives of the type Ph2P(O)CH(R)OH, through P(III)-N bond cleavage. The N-bridged bis(phosphine oxide) nPrN(CH2P(O)Ph 2)2 readily forms chelate complexes with U(VI), Th(IV) and Gd(III) derivatives.
Synthesis, characterization and the crystal structures of novel achiral and chiral α-ferrocenyl α-aminophosphine oxides
Du, Ling-Zhi,Gong, Jun-Fang,Zhu, Yu,Wu, Yang-Jie,Song, Mao-Ping
, p. 529 - 532 (2008/10/09)
Novel achiral α-ferrocenyl α-aminophosphine oxides (2a-2e) have been prepared by the reaction of ferrocenylaldimines (1a-1e) with Ph2PLi at room temperature in 63-92% yield. Similarly, starting from l-phenylalaninol derived ferrocenylaldimine (
