868365-96-2

Usage

Uses

Used in Coordination Chemistry:
[12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a ligand in coordination chemistry for its ability to form stable complexes with metal ions. The presence of nitrogen and sulfur atoms in the macrocyclic ring allows for versatile coordination geometries and strong binding affinities.
Used in Molecular Recognition:
In molecular recognition, [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a receptor due to its unique structure and the potential for selective binding with specific target molecules. The combination of nitrogen and sulfur atoms in the macrocyclic ring provides opportunities for various non-covalent interactions, such as hydrogen bonding and van der Waals forces, which can be exploited for molecular recognition.
Used in Biochemical Studies:
[12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a tool in biochemical research for its potential to interact with biological macromolecules, such as proteins and nucleic acids. [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide's structural features may allow it to modulate biological processes or serve as a probe for studying the structure and function of biomolecules.
Used in Biophysical Studies:
In biophysical studies, [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a model compound to investigate the properties of macrocyclic systems and their interactions with other molecules. [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide's unique structure can provide insights into the behavior of similar macrocyclic compounds and their potential applications in various fields.
Used in Pharmaceutical Industry:
[12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a lead compound in the pharmaceutical industry for its potential therapeutic applications. [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide's unique structure and properties may be harnessed to develop new drugs targeting specific biological processes or to improve the delivery and efficacy of existing drugs.
Used in Material Science:
In material science, [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide is used as a building block for the development of new materials with unique properties. [12]aneNS3, N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]dansylamide's structural features may be utilized to create materials with specific characteristics, such as enhanced stability, selectivity, or responsiveness to external stimuli.

InChI:InChI=1/C23H35N3O2S4/c1-25(2)22-8-3-7-21-20(22)6-4-9-23(21)32(27,28)24-10-5-11-26-12-14-29-16-18-31-19-17-30-15-13-26/h3-4,6-9,24H,5,10-19H2,1-2H3

Upstream product

• 868365-94-0 3-(1,4,7-trithia-10-aza-cyclododec-10-yl)-propylamine 
• 605-65-2 5-(dimethylamino)naphth-1-ylsulfonyl chloride 
• 122011-96-5 7-aza-1,4,10-trithiacyclododecane 
• 868365-93-9 3-(1,4,7-trithia-10-aza-cyclododec-10-yl)-propionitrile 

Relevant academic research and scientific papers

Coordination chemistry of N-aminopropyl pendant arm derivatives of mixed N/S-, and N/S/O-donor macrocycles, and construction of selective fluorimetric chemosensors for heavy metal ions

The coordination chemistry of the N-aminopropyl pendant arm derivatives (L1c-4c) of the mixed donor macrocyclic ligands [12]aneNS 2O, [12]aneNS3, [12]aneN2SO, and [15]aneNS 2O2 (L1a-4a) towards CuII, Zn II, CdII, HgII, and PbII in aqueous solution has been investigated. The protonation and stability constants with the aforementioned metal ions were determined potentiometrically and compared, where possible, with those of the unfunctionalised macrocycles. The measured values show that HgII and CuII in water have the highest affinity for all ligands considered, with the N-aminopropyl pendant arm weakly coordinating the metal centres. Crystals suitable for X-ray diffraction analysis were grown for the perchlorate salt (H2L 1c)(ClO4)2·dmf, and for the 1:1 complexes [Cd(L3a)(NO3)2] (1), [Cu(L 4a)(dmf)](ClO4)2 (2), [Zn(L 1c)(ClO4)]ClO4 (3), [Cd(L1c)(NO 3)]NO3 (4), and [Hg(L2c)](ClO4) 2 (5). Their structures show the macrocyclic ligands adopting a folded conformation, which for the 12-membered systems can be either [2424] or [3333] depending on the nature of the metal ion. L1c-4c were also functionalised at the primary amino pendant group with different fluorogenic subunits. In particular the N-dansylamidopropyl (Lnd, n = 1-4), and the N-(9-anthracenylmethyl)aminopropyl (Lne, n = 1, 2, 4, Scheme 1) pendant arm derivatives of L1a-4a were synthesised and their optical responses to the above mentioned metal ions were investigated in MeCN/H 2O (4: 1 v/v) solutions. The Royal Society of Chemistry 2005.