868367-16-2Relevant academic research and scientific papers
Functionalization of bicyclic 2-pyridones targeting pilus biogenesis in uropathogenic Escherichia coli
Pemberton, Nils,Pinkner, Jerome S.,Jones, Jennifer M.,Jakobsson, Lotta,Hultgren, Scott J.,Almqvist, Fredrik
, p. 4543 - 4546 (2008/02/03)
Substituted bicyclic 2-pyridones, termed pilicides, prevent pilus assembly in uropathogenic Escherichia coli. Based on the bioactive methyl ester protected 2-pyridone 4, further functionalization at C-6 has yielded a set of new compounds, which have been
AMINO METHYLATED 2-PYRIDINONES
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Page/Page column 42; 43, (2008/06/13)
Novel amino methylated 2-pyridinones, precursors, intermediates, and derivatives; the methods for the preparation of the same; uses of the same for inhibiting pili formation in bacteria; and pharmaceutical compositions comprising these compounds are descr
