868367-20-8Relevant academic research and scientific papers
Microwave-assisted synthesis of highly substituted aminomethylated 2-pyridones
Pemberton, Nils,Aberg, Veronica,Almstedt, Hanna,Westermark, Andreas,Almqvist, Fredrik
, p. 7830 - 7835 (2004)
By employing microwave-assisted organic synthesis (MAOS) efficient conditions to introduce aminomethylene substituents in highly substituted bicyclic 2-pyridones have been established. Primary amino methylene substituents were introduced via a cyanodehalo
Regioselective halogenations and subsequent Suzuki-Miyaura coupling onto bicyclic 2-pyridones
Bengtsson, Christoffer,Almqvist, Fredrik
supporting information; experimental part, p. 972 - 975 (2010/04/30)
(Chemical Equation Presented) A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki - Miyaura couplings. This approach can advantageously be used to synthesize focused libraries of substituted ring-fused 2-pyridones, a class of compounds with novel antibacterial properties.
