86851-83-4

Upstream product

• 83562-30-5 2-Butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-en-1-one 
• 83562-28-1 1-benzyl-7-butyl-1-azaspirocyclo<5.5>undec-7-ene 
• 88367-25-3 1-Acetoxy-2-butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-ene 
• 85612-38-0 2-Butyl-3-<4-(p-tolylsulfonoxy)butyl>cyclohex-2-en-1-ol 
• 86817-84-7 1-Acetoxy-2-butyl-3-<4-(benzylamino)butyl>cyclohex-2-ene 
• 83562-29-2 2-Butyl-3-(4-hydroxybutyl)-2-cyclohexen-1-one 
• 56459-18-8 2-butyl-3-ethoxy-2-cyclohexen-1-one 
• 83562-25-8 3-(4-Benzylamino-butyl)-2-butyl-cyclohex-2-enone 
• 83562-27-0 3-(4-Benzylamino-butyl)-2-butyl-cyclohex-2-enol 

Downstream Products

• 55228-77-8 (+/-)-depentylperhydrohistrionicotoxin 
• 83562-26-9 1-Benzyl-7-butyl-1-aza-spiro[5.5]undecan-8-one 
• 83562-34-9 (6SR,7SR)-7-n-butyl-N-benzyl-1-azaspiro<5.5>undecan-8-one 
• 83562-26-9 (6S,7R)-1-Benzyl-7-butyl-1-aza-spiro[5.5]undecan-8-one 
• 83562-31-6 (6RS,7SR,8SR)-7-n-Butyl-N-benzyl-1-azaspiro<5.5>undecan-8-ol 
• 86817-86-9 O-acetyl-N-benzyldepentylperhydrohistrionicotoxin 
• 86817-86-9 O-acetyl-N-benzyldepentylperhydrohistrionicotoxin 

Relevant academic research and scientific papers

Synthesis of (+/-)-Depentylperhydrohistrionicotoxin

Palladium(0)-catalysed cyclisation of 3-acetoxy-1-(4-aminoalkyl)cyclohexenes provides convenient access to the 1-azaspiroundecane ring system found in the histrionicotoxins.Hydroboration of the 7-butyl derivative (4; R1 = Bun, R

Trimethylsilyl Iodide Catalyzed Spirocyclization of Amines. Synthesis of Perhydrohistrionicotoxin

A trimethylsilyl iodide catalyzed Michael reaction of an enone amine and a trimethylsilyl iodide catalyzed SN2' spirocyclization of an allylic alcohol amine are the crucial reactions in two new syntheses of perhydrohistrionicotoxin.