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2-(Trifluoromethyl)pyrrolidine, hydrochloride is a chemical compound that features a pyrrolidine ring with a trifluoromethyl group attached to it, along with a hydrochloride salt. It is recognized for its distinctive structural attributes, which are beneficial for binding to biological targets in the realm of drug development. 2-(Trifluoromethyl)pyrrolidine, hydrochloride has garnered attention for its potential applications in treating a range of diseases, including cancer and infectious diseases, and has also been explored as a reagent in organic synthesis for its capacity to incorporate the trifluoromethyl group into various molecules, thereby enhancing its value in pharmaceutical and agrochemical industries.

868623-97-6

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868623-97-6 Usage

Uses

Used in Pharmaceutical Industry:
2-(Trifluoromethyl)pyrrolidine, hydrochloride is utilized as a building block for the synthesis of various pharmaceuticals due to its unique structural properties that facilitate binding to biological targets, which is crucial for drug development.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(Trifluoromethyl)pyrrolidine, hydrochloride serves as a key component in the creation of agrochemicals, leveraging its structural features to improve the effectiveness of these compounds in agricultural applications.
Used in Drug Development:
2-(Trifluoromethyl)pyrrolidine, hydrochloride is employed as a potential therapeutic agent for the treatment of various diseases such as cancer and infectious diseases, capitalizing on its ability to engage with biological targets to combat these conditions.
Used in Organic Synthesis as a Reagent:
2-(Trifluoromethyl)pyrrolidine, hydrochloride is used as a reagent in organic synthesis to introduce the trifluoromethyl group into different molecules, which is an important modification for enhancing the properties of these molecules in both pharmaceutical and agrochemical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 868623-97-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,6,2 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 868623-97:
(8*8)+(7*6)+(6*8)+(5*6)+(4*2)+(3*3)+(2*9)+(1*7)=226
226 % 10 = 6
So 868623-97-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H8F3N.ClH/c6-5(7,8)4-2-1-3-9-4;/h4,9H,1-3H2;1H

868623-97-6 Well-known Company Product Price

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  • Aldrich

  • (725870)  (±)-2-(Trifluoromethyl)pyrrolidinehydrochloride  ≥96.0%

  • 868623-97-6

  • 725870-500MG

  • 1,064.70CNY

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868623-97-6Relevant academic research and scientific papers

The reaction of cyclic imines with the Ruppert-Prakash reagent. Facile approach to α-trifluoromethylated nornicotine, anabazine, and homoanabazine

Shevchenko, Nikolay E.,Vlasov, Katja,Nenajdenko, Valentine G.,R?schenthaler, Gerd-Volker

experimental part, p. 69 - 74 (2011/02/27)

We have demonstrated that the Ruppert-Prakash reagent is able to react with a number of cyclic imines under acidic condition to afford the corresponding α-trifluoromethyl derivatives of nitrogen heterocycles. 5-7-Membered cyclic imines bearing various alkyl, aryl or heterocyclic group were successfully involved in this transformation. Novel trifluoromethylated analogues of nicotine, anabasine, and homoanabasine alkaloids were synthesized.

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