868623-97-6 Usage
General Description
2-(Trifluoromethyl)pyrrolidine hydrochloride is a chemical compound consisting of a pyrrolidine ring with a trifluoromethyl group attached to it, and a hydrochloride salt. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 2-(Trifluoromethyl)pyrrolidine, hydrochloride is known for its unique structural properties, which make it useful for binding to biological targets in drug development. It has been studied for its potential use in the treatment of various diseases, including cancer and infectious diseases. Additionally, it has also been investigated as a reagent in organic synthesis due to its ability to introduce the trifluoromethyl group into different molecules, making it a valuable tool for the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 868623-97-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,6,2 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 868623-97:
(8*8)+(7*6)+(6*8)+(5*6)+(4*2)+(3*3)+(2*9)+(1*7)=226
226 % 10 = 6
So 868623-97-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H8F3N.ClH/c6-5(7,8)4-2-1-3-9-4;/h4,9H,1-3H2;1H
868623-97-6Relevant articles and documents
The reaction of cyclic imines with the Ruppert-Prakash reagent. Facile approach to α-trifluoromethylated nornicotine, anabazine, and homoanabazine
Shevchenko, Nikolay E.,Vlasov, Katja,Nenajdenko, Valentine G.,R?schenthaler, Gerd-Volker
experimental part, p. 69 - 74 (2011/02/27)
We have demonstrated that the Ruppert-Prakash reagent is able to react with a number of cyclic imines under acidic condition to afford the corresponding α-trifluoromethyl derivatives of nitrogen heterocycles. 5-7-Membered cyclic imines bearing various alkyl, aryl or heterocyclic group were successfully involved in this transformation. Novel trifluoromethylated analogues of nicotine, anabasine, and homoanabasine alkaloids were synthesized.
