868636-76-4

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Pyridinecarboxylic acid, 5-chloro-2-Methyl-, ethyl ester is used as an intermediate in the pharmaceutical industry for the production of various drugs. Its unique structure allows it to be a key component in the synthesis of compounds with therapeutic potential.
Used in Agrochemical Production:
In the agrochemical industry, 3-Pyridinecarboxylic acid, 5-chloro-2-Methyl-, ethyl ester is utilized as an intermediate in the synthesis of pesticides. Its properties contribute to the development of effective and targeted pest control agents.
Used in Research and Development:
3-Pyridinecarboxylic acid, 5-chloro-2-Methyl-, ethyl ester is used as a building block in research and development for the synthesis of novel compounds with potential biological activity. Its unique structure provides a foundation for the creation of new molecules that may have applications in various fields.
Used in Disease Treatment and Drug Development:
3-Pyridinecarboxylic acid, 5-chloro-2-Methyl-, ethyl ester has been studied for its potential applications in the treatment of various diseases. Its unique properties make it a promising candidate for the development of new drugs and therapeutic agents.

Upstream product

• 823-96-1 Trimethylboroxine 
• 148065-10-5 ethyl 5-chloro-2-chloronicotinate 
• 59782-85-3 2,5-dichloronicotinic acid 
• 141-97-9 ethyl acetoacetate 

Relevant academic research and scientific papers

A 5 - bromo -2 - methyl nicotinic acid ethyl ester

The invention discloses a 5 - bromo - 2 - methyl nicotinic acid ethyl ester synthetic method, comprises the following steps: the acetyl ethyl acetate and alkali A adding solvent in the B enolizable; adding intermediate III and DABCO reaction; adding ammonium to cyclization; adding water quenching, organic solvent extraction C; removing the organic solvent to be crystalline crude product shall C; to be crystalline crude product recrystallized from 5 - bromo - 2 - methyl nicotinic acid ethyl ester; the invention to Meck development of 5 - chloro - 2 - methyl nicotinic acid ethyl ester is based on, through changing the reaction solvent and reduce the reaction temperature, significantly improves the stability of the intermediate III, so that the reaction can be smoothly to obtain the product, after treatment through recrystallization purification, thus avoiding the time-consuming column chromatography process, the average yield of 70%, the purity of 99.0% or more, is suitable for the large-scale industrial production.

NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES

Disclosed herein are 5 or 8-substituted imidazo[l,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[l,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8- substituted imidazo[l,5-a]pyridines that can be useful for inhibiting indoleamine 2,3- dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.

COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS

The instant invention relates to a combination of an EP4-receptor antagonist and an alpha-2-delta ligand, and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof and their use in the treatment of pain, particularly inflammatory,

SUBSTITUTED METHYL ARYL OR HETEROARYL AMIDE COMPOUNDS

This invention provides a compound of the formula (I), wherein X represents a carbon atom or the like: Y represents imino, or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 in