868660-49-5Relevant academic research and scientific papers
Synthesis and antibacterial activity of N-[2-(5-bromothiophen-2-yl)-2- oxoethyl] and N-[(2-5-bromothiophen-2-yl)-2-oximinoethyl] derivatives of piperazinyl quinolones
Foroumadi, Alireza,Emami, Saeed,Mehni, Massood,Moshafi, Mohammad Hassan,Shafiee, Abbas
, p. 4536 - 4539 (2005)
A series of N-[2-(5-bromothiophen-2-yl)-2-oxoethyl] and N-[2-(5-bromothiophen-2-yl)-2-oximinoethyl]derivatives of piperazinyl quinolones were synthesized and evaluated for antimicrobial activity against Gram-positive and Gram-negative microorganisms. Some of these derivatives exhibit comparable or better activity against Gram-positive bacteria, Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis, than ciprofloxacin, norfloxacin and enoxacine as reference drugs.
