86867-31-4

Upstream product

• 110-91-8 morpholine 
• 949-01-9 1-(morpholin-4-yl)-2-phenylethanethione 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 952614-35-6 3-(4-acetylphenyl)-2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3H-quinazolin-4-one 
• 952613-94-4 2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3-phenyl-3H-quinazolin-4-one 
• 952614-12-9 2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3-p-tolyl-3H-quinazolin-4-one 
• 952614-30-1 3-(4-chlorophenyl)-2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3H-quinazolin-4-one 
• 952614-16-3 3-(2-methoxyphenyl)-2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3H-quinazolin-4-one 
• 952614-00-5 2-(5-(morpholin-4-yl)-4-phenylthiophen-2-yl)-3-o-tolyl-3H-quinazolin-4-one 

Relevant academic research and scientific papers

Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-k{cyrillic}B and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer ag

In an attempt to discover novel inhibitors of NF-κB and AP-1 mediated transcriptional activation utilizing the concept of chemical lead based medicinal chemistry and bioisosterism a series of 2-(2,3-disubstituted-thiophen-5-yl)-3H-quinazolin-4-one analogs