868686-05-9Relevant academic research and scientific papers
Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter
Zeng, Fanxing,Jarkas, Nachwa,Stehouwer, Jeffrey S.,Voll, Ronald J.,Owens, Michael J.,Kilts, Clinton D.,Nemeroff, Charles B.,Goodman, Mark M.
, p. 783 - 793 (2008/09/17)
Six new (S, S)-enantiomers of reboxetine derivatives were synthesized and their binding affinities were determined via competition binding assays in cells expressing the human norepinephrine transporter (NET), serotonin transporter (SERT) or dopamine tran
Substituted morpholine compounds for the treatment of central nervous system disorders
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Page/Page column 45, (2010/02/14)
This invention relates to compounds of the formulae I wherein R1-R8, A, X, and Z are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system disorders.
