86870-34-0Relevant academic research and scientific papers
Synthesis of novel imidazo[2,1-b][1,3,4]thiadiazoles appended to sydnone as anticancer agents
Tegginamath, Gireesh,Kamble, Ravindra R.,Taj, Tasneem,Kattimani, Pramod P.,Meti, Gangadhar Y.
, p. 4367 - 4375 (2013)
A novel series of 3-aryl-4{6′-(6′′-substituted-coumarin- 3′′-yl) imidazo[2,1-b][1,3,4]thiadiazol-2′-yl}-sydnones 5h-5s were synthesized and screened for their anticancer and DNA cleavage activities and analyzed for pharmacological parameters such as toxicity, drug-likeliness, and drug score for oral bioavailability. In vitro toxicity assay was carried out by assessing the survival E. coli AB1157 (wild type) cultures. Some of the compounds have shown significant anticancer activities also.
Design, docking studies and molecular iodine catalyzed synthesis of benzo[a]xanthen-one derivatives as hyaluronidase inhibitors
Kumbar, Mahadev N.,Kamble, Ravindra R.,Kamble, Atulkumar A.,Joshi, Shrinivas D.,Dixit, Sheshagiri R.,Hoskeri, Joy
, p. 2451 - 2460 (2016/10/25)
A series of novel benzo[a]xanthen-11(12H)-one derivatives 4a–m were designed and subjected to docking studies. The title compounds were synthesized from 3-aryl-4-formylsydnones 1a–m, β-naphthol and dimedone in presence of molecular iodine as a catalyst an
Synthesis of novel 2-(3′-aryl-sydnon-4′-ylidene)-5′- substituted-[1,3,4]-thiadiazolylamines and [1,3,4]-thiadiazol-2′-yl-3-oxo- [1,2,4]-triazoles as antimicrobial agents
Bansode, Soujanya,Kamble, Ravindra
body text, p. 867 - 873 (2012/08/14)
The title compounds (3g-n) and (6g-n) were synthesized using 3-arylsydnones as synthons, and the structures were confirmed by IR, 1H NMR, FAB mass and CHN analysis. These compounds were evaluated for their antibacterial and the antifungal activ
