86872-78-8Relevant articles and documents
Reactions of l, 3-diethyl-2-thiobarbituric acid with aldehydes: Formation of arylbis(l, 3-diethyl-2-thiobarbitur-5-yl)methanesf and crystallographic evidence for ground state polarisation in l, 3-diethyl-5-[4-(dimethylamino)benzylidene]-2-thiobarbituric a
Adamson, Jason,Coe, Benjamin J.,Grassam, Helen L.,Jeffery, John C.,Coles, Simon J.,Hursthouse, Michael B.
, p. 2483 - 2488 (1999)
The reactions of 1, 3-diethyl-2-thiobarbituric acid (detba) in ethanol at room temperature with 4-(dimethylamino)benzaldehyde (dmabza) or cinnamaldehyde afford the Knoevenagel products 3 and 4, respectively. Under identical conditions, pyridine-4-carbalde
Acetylcholinesterase and butyrylcholinesterase inhibitory activities of 5-arylidene-N, N-diethylthiobarbiturates
Khan, Momin,Rehman, Munir Ur,Qadir, Naveed,Ashraf, Muhammad,Ismail, Tayaba,Ismail, Muhammad,Kanwal,Salar, Uzma,Khan, Khalid Mohammed,Perveen, Shahnaz
, p. 134 - 140 (2020/02/13)
5-Arylidene-N,N-diethylthiobarbiturates 1-25 were evaluated for their potential against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes and displayed varying degree of inhibition. Based on the IC50 values, compound 6 (ICsu
Synthesis, molecular modeling and biological evaluation of 5-arylidene- N,N-diethylthiobarbiturates as potential α-glucosidase Inhibitors
Ashraf, Muhammad,Hameed, Abdul,Hussain, Zahid,Khan, Abbas,Khan, Iltaf,Khan, Khalid M.,Khan, Momin,Khan, Sehrish,Perveen, Shahnaz,Rahman, Jameel,Shams, Sulaiman,Ul Mulk, Amir,Ur Rahman, Anis,Wadood, Abdul,Zaman, Khair
, p. 175 - 185 (2019/07/12)
Background: Barbituric acid derivatives are a versatile group of compounds which are identified as potential pharmacophores for the treatment of anxiety, epilepsy and other psychiatric disorders. They are also used as anesthetics and have sound effects on
