868761-01-7Relevant articles and documents
Synthesis and transformation of [difluoro(phenylseleno)methyl]- trimethylsilane
Qin, Ying-Ying,Qiu, Xiao-Long,Yang, Yan-Yan,Meng, Wei-Dong,Qing, Feng-Ling
, p. 9040 - 9043 (2005)
A novel and efficient strategy was developed to synthesize [difluoro(phenylseleno)methyl]trimethylsilane (PhSeCF2-TMS, 2), which was further utilized as a nucleophilic difluoromethylating reagent to incorporate the difluoro-(phenylseleno)methyl (PhSeCF2) group into carbonyl compounds in good yields. The resulting PhSeCF2-containing alcohols 3 could be conveniently converted into corresponding difluoromethyl alcohols 4 by a radical deselenylation.