86881-97-2

Basic information

• Product Name: 2,3-dihydro-4-(2'-hydroxy-5'-methylphenyl)-2-phenyl-1,5-benzothiazepine
• CAS NO: 86881-97-2
• Molecular Weight: 345.465
• Mol File: 86881-97-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-dihydro-4-(2'-hydroxy-5'-methylphenyl)-2-phenyl-1,5-benzothiazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-4-(2'-hydroxy-5'-methylphenyl)-2-phenyl-1,5-benzothiazepine(86881-97-2)
• EPA Substance Registry System: 2,3-dihydro-4-(2'-hydroxy-5'-methylphenyl)-2-phenyl-1,5-benzothiazepine(86881-97-2)

Safety Data

• Hazardous Substances Data: 86881-97-2(Hazardous Substances Data)

Upstream product

• 1775-98-0 2'-hydroxy-5'-methylchalcone 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 86882-29-3 2,3-dihydro-4-(2'-hydroxy-5'-methylphenyl)-2-phenyl-1,5-benzothiazepine-1,1-dioxide 

Relevant articles and documents

Synthesis of 2,4-Diaryl-2,3-dihydro-1,5-benzothiazepines & their 1,1-Dioxides as antibacterial Agents

o-Aminothiophenol reacts with chalkones (I) in methanol-acetic acid to give 3-(2-aminophenylmercapto)-3-arylpropiophenones (II) which immediately undergo cyclization in situ to give 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines (IIIa).Compounds IIIa are easily oxidised to the corresponding 1,1-dioxides (IV) by H2O2 (30percent) in gl. acetic acid.A few compunds have been screened for their antibacterial activity against S. aureus, S. typhi., V.Comma and E. coli.