868846-96-2Relevant academic research and scientific papers
Novel chemistry of β-carbolines. Expedient synthesis of polycyclic scaffolds
González-Gómez, álvaro,Domínguez, Gema,Pérez-Castells, Javier
supporting information; experimental part, p. 3378 - 3391 (2009/09/06)
Functionalization of β-carbolines is a challenge as numerous natural alkaloids with different biological activities present this heterocycle. The RCM is used herein with allyl-, vinyl-, ethynyl-, and propargyl-β-carbolines to generate additionally fused h
Enyne and dienyne metathesis reactions in β-carbolines
González-Gómez, álvaro,Domínguez, Gema,Castells, Javier Pérez
, p. 7267 - 7270 (2007/10/03)
New indolic enynes and dienynes, based on the β-carboline system, give metathesis products with ruthenium catalysts. The synthesis of the starting materials is readily achieved from tryptamine. The tuning up of the conditions for the metathesis is discussed. Cascade metathesis gives an oxidized pentacyclic product.
