86896-32-4Relevant academic research and scientific papers
Experiments Directed Towards the Synthesis of Anthracyclinones. VII. Model Studies with Allyl Naphthalenyl Ethers
Boddy, Ian K.,Cambie, Richard C.,Dixon, Graham,Rutledge, Peter S.,Woodgate, Paul D.
, p. 803 - 813 (2007/10/02)
The Claisen rearrangement of some allyl naphthalen-1-yl ethers has been examined, together with methods for modification of the resulting 2-allyl side chain.Isomerisation of the C-allyl substituent to a prop-1-enyl group followed by ozonolysis gives a formyl derivative, while ozonolysis of a 2-(2-methylprop-2-enyl) moiety or mercuriation of a 2-(-2-chloroprop-2-enyl) substituent leads to an acetonyl derivative.Treatment of phenols with iodine(I) acetate and an excess of silver(I) acetate gives 4-hydroxyaryl acetates, probably via dienone intermediates.
