869005-58-3

Upstream product

• 83141-42-8 2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde 
• 5754-34-7 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane 
• 869005-51-6 O-isopropylidene-1-(2',5'-dimethoxyphenyl)-1-pentene-4,5-diol 

Downstream Products

• 869005-78-7 2-amino-3-cyano-4-[3'-(2',3'-dimethoxyphenyl)propyl]-furan 
• 869005-71-0 5-(2',5'-dimethoxyphenyl)-1-hydroxy-2-pentanone 
• 869005-65-2 5-(2',5'-dimethoxophenyl)-1,2-pentanediol 

Relevant academic research and scientific papers

Synthesis of three carbon atom bridged 2,4-diaminopyrrolo[2,3-d]- pyrimidines as nonclassical dihydrofolate reductase inhibitors

A series of seven nonclassical three carbon atom bridged 2,4-diamino-5-substituted-pyrrolo[2,3-d]-pyrimidines 1a-g were synthesized as potential inhibitors of dihydrofolate reductase. Selective oxidation of diols 7a-g affords oe-hydroxy ketones 8a-g. Subs