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Synthesis of 3-Carboxyisocoumarins: Wittig Reactions of Phthalaldehydic Acid
Narasimhan, N. S.,Kusurkar, S. S.
, p. 345 - 348 (2007/10/02)
Wittig reaction of phthalaldehydic acid with Ph3P=CHCOOEt and Ph3P=C(Br)COOEt provides the phthalides 1 and 6, 7 and 9 respectively.Phthalides (1) and (6) on hydrolysis furnish the ortho-carboxycinnamic acids (3) and (4).However, attempted thermal cyclisa
