869085-19-8

Basic information

• Product Name: 2-bromophenyl 1-cyclohexyl-2-propynyl ether
• Synonyms: 2-bromophenyl 1-cyclohexyl-2-propynyl ether
• CAS NO: 869085-19-8
• Molecular Weight: 293.203
• Mol File: 869085-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromophenyl 1-cyclohexyl-2-propynyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromophenyl 1-cyclohexyl-2-propynyl ether(869085-19-8)
• EPA Substance Registry System: 2-bromophenyl 1-cyclohexyl-2-propynyl ether(869085-19-8)

Safety Data

• Hazardous Substances Data: 869085-19-8(Hazardous Substances Data)

Upstream product

• 2043-61-0 cyclohexanecarbaldehyde 
• 95-56-7 2-hydroxybromobenzene 
• 97563-45-6 1-cyclohexylprop-2-yn-1-ol 

Downstream Products

• 869085-16-5 2-bromophenyl 1-cyclohexyl-2-propenyl ether 

Relevant articles and documents

Intramolecular carbolithiation of allyl o-lithioaryl ethers: A new enantioselective synthesis of functionalized 2,3-dihydrobenzofurans

A new and easy method for the diastereoselective synthesis of 3-functionalized 2,3-dihydrobenzofuran derivatives from allyl 2-bromoaryl ethers is described. The key step of this transformation involves an intramolecular carbolithiation reaction of allyl 2-lithioaryl ethers. The substituents in both the allyl and the aryl moieties play an important and decisive role in stopping the reaction at the benzofuran thus avoiding a γ-elimination reaction. Finally, this process is amenable to the synthesis of enantiomerically enriched compounds by using ( - )-sparteine as a chiral inductor.