869099-20-7

Basic information

• Product Name: C₂₆H₂₁F₆NO₃S₂
• CAS NO: 869099-20-7
• Molecular Weight: 573.58
• Mol File: 869099-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₁F₆NO₃S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₁F₆NO₃S₂(869099-20-7)
• EPA Substance Registry System: C₂₆H₂₁F₆NO₃S₂(869099-20-7)

Safety Data

• Hazardous Substances Data: 869099-20-7(Hazardous Substances Data)

Upstream product

• 869099-03-6 C₂₁H₁₇F₆NO₃S 
• 636-72-6 2-thiophenemethanol 

Relevant articles and documents

Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors

LFA-1 ICAM inhibitors based on ortho- and meta-phenol templates were designed and synthesized by Mitsunobu chemistry. The selection of targets was guided by X-ray co-crystal data, and led to compounds which showed an up to 30-fold increase in potency over reference compound 1 in the LFA-1/ICAM1-Ig assay. The most active compound exploited a new hydrogen bond to the I-domain and exhibited subnanomolar potency.