869101-67-7

Basic information

• Product Name: {5-(4-benzyloxy-3-methoxy-phenyl)-1-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-pentyl}-butyl-amine
• Synonyms: {5-(4-benzyloxy-3-methoxy-phenyl)-1-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-pentyl}-butyl-amine
• CAS NO: 869101-67-7
• Molecular Weight: 595.822
• Mol File: 869101-67-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {5-(4-benzyloxy-3-methoxy-phenyl)-1-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-pentyl}-butyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: {5-(4-benzyloxy-3-methoxy-phenyl)-1-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-pentyl}-butyl-amine(869101-67-7)
• EPA Substance Registry System: {5-(4-benzyloxy-3-methoxy-phenyl)-1-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-pentyl}-butyl-amine(869101-67-7)

Safety Data

• Hazardous Substances Data: 869101-67-7(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 458-37-7 curcumin 
• 869101-60-0 O,O-di-t-butyloxycarbonylhexahydrocurcumin 
• 869101-61-1 1,7-bis(4-benzyloxy-3-methoxyphenyl)-3-heptanone 
• 685530-97-6 1,7-bis(4-hydroxy-3-methoxy-phenyl)heptan-3-one 

Relevant articles and documents

Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs

Seven diarylheptylamine (12a-g) and four diarylheptanoid analogs (3-5, 9), structurally related to the natural anti-inflammatory agent oregonin (1), have been prepared from curcumin (2) for evaluation of their activity against the expression of iNOS and COX-2. Diarylheptylamine 12b and diarylheptanoid analogs can inhibit iNOS and COX-2 responses of LPS, although less potently than 1. These compounds, however, possess stronger potency than 1 against COX-2-derived PGE2 formation, of which hexahydrocurcumin (4) is the most potent one with an IC50 value of 0.7 μM.