869105-11-3Relevant academic research and scientific papers
Construction of two vicinal quaternary carbons by asymmetric allylic alkylation: Total synthesis of hyperolactone C and (-)-biyouyanagin A
Du, Chao,Li, Liqi,Li, Ying,Xie, Zhixiang
supporting information; experimental part, p. 7853 - 7856 (2010/04/05)
Call on triple A: Palladium-catalyzed asymmetric allylic alkylation (Pd-AAA; see scheme) has enabled a concise and efficient synthesis of hyperolacto ne C and (-)-biyouyanagin A in only six (20% Overall yield) and seven (8% overall yield) steps, respectively. The enantiomers of these natural products were also prepared by exploiting the same methodology.
