869116-14-3Relevant articles and documents
The synthesis and evaluation of 10- and 12-membered ring benzofused enediyne amino acids
Du, Yanming,Creighton, Christopher J.,Yan, Zhengyin,Gauthier, Diane A.,Dahl, John P.,Zhao, Boyu,Belkowski, Stanley M.,Reitz, Allen B.
, p. 5936 - 5948 (2007/10/03)
The enediyne moiety is a versatile functional group found in natural anticancer and anti-infective agents, undergoing the Bergman cyclization reaction to afford a diradical which cleaves double-stranded DNA. We have incorporated the enediyne group into 10