869206-35-9Relevant academic research and scientific papers
Domino reaction of 2,3-epoxy-1-alcohols and PIFA in the presence of H 2O and the concise synthesis of (+)-tanikolide
Kita, Yasuyuki,Matsuda, Satoshi,Fujii, Eri,Horai, Mai,Hata, Kayoko,Fujioka, Hiromichi
, p. 5857 - 5860 (2005)
(Chemical Equation Presented) Lactols are prepared by a single operation, in which 2,3-epoxy-1-alcohols are treated with phenyliodine(III) bis(trifluoroacetate) (PIFA) in the presence of H2O. Thus, an efficient domino three- or four-step sequen
Facile and efficient synthesis of lactols by a domino reaction of 2,3-epoxy alcohols with a hypervalent iodine(III) reagent and its application to the synthesis of lactones and the asymmetric synthesis of (+)-tanikolide
Fujioka, Hiromichi,Matsuda, Satoshi,Horai, Mai,Fujii, Eri,Morishita, Maiko,Nishiguchi, Natsuko,Hata, Kayoko,Kita, Yasuyuki
, p. 5238 - 5248 (2008/02/10)
The domino reaction of 2,3-epoxy-1-alcohol derivatives, namely tetrasubstituted 2,3-epoxy-1 -alcohols and 2- or 3-alkyl trisubstituted 2,3-epoxy-1-alcohols, with PhI(OCOCF3)2 in the presence of H2O is described in detail.
