869210-40-2Relevant academic research and scientific papers
Asymmetric synthesis of 4′-quaternary 2′-deoxy-3′- and -4′-epi-β-C- and -N-nucleosides
Enders, Dieter,Hieronymi, Antje,Raabe, Gerhard
experimental part, p. 1545 - 1558 (2009/04/03)
A versatile and efficient route to both enantiomers of 4′-quaternary 2′-deoxy-3′- and -4′-epi-β-C- and -N-nucleosides is described. The asymmetric synthesis involves the SAMP/RAMP-hydrazone α-alkylation methodology and diastereoselective nucleophilic 1,2-
Asymmetric synthesis of 4′-quaternary 2′-deoxy-3′-epi- β-C-nucleosides
Enders, Dieter,Hieronymi, Antje,Ridder, André
, p. 2391 - 2393 (2007/10/03)
An efficient diastereo- and enantioselective synthesis of 4′-quaternary 2′-deoxy-3′-epi-β-C-nucleosides is described employing the RAMP-hydrazone methodology to establish the first stereocentre. Further key steps include diastereoselective nucleophilic 1,
