869304-98-3Relevant academic research and scientific papers
Synthesis of non-symmetric bisoxazoline compounds. An easy way to reach tailored chiral ligands
Garcia, Jose I.,Mayoral, Jose A.,Pires, Elisabet,Villalba, Isabel
, p. 2270 - 2275 (2007/10/03)
Bisoxazoline compounds have been used as chiral catalyst ligands in a wide variety of reactions. A great deal of effort has been aimed at the synthesis of C2-symmetric bisoxazolines but very few references exist for non-symmetric ones. As part of our studies into the possible usefulness of non-symmetric bisoxazolines, we report an easy method for the synthesis of bisoxazoline compounds bearing different substituents in each oxazoline ring.
An efficient and general one-pot method for the synthesis of chiral bis(oxazoline) and pyridine bis(oxazoline) ligands
Cornejo,Fraile,García,Gil,Martínez-Merino,Mayoral,Pires,Villalba
, p. 2321 - 2324 (2007/10/03)
An expeditious method for the synthesis of chiral box and pybox ligands is reported. The approach is based on a one-pot condensation reaction of chiral β-amino alcohols with a dinitrile using stoichiometric or catalytic amounts of zinc triflate. Yields gr
