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1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methylis an organic compound with the chemical formula C9H10N4. It is a heterocyclic amine that features a pyrrolo-pyridine core with a methyl group attached to the nitrogen atom at the 1-position. 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methylis known for its potential applications in the synthesis of various pharmaceutically relevant molecules.
Used in Pharmaceutical Industry:
1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methylis used as a reagent for the preparation of hexahydropyrimidone containing quinoline compounds. These compounds are of interest as c-Met kinase inhibitors, which are important targets for the development of drugs to treat various cancers and other diseases. The c-Met kinase plays a crucial role in cell growth, proliferation, and survival, and its dysregulation has been implicated in the progression of several malignancies. By inhibiting this kinase, the synthesized compounds may help in controlling tumor growth and metastasis.

869335-48-8

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869335-48-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 869335-48-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,3,3 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 869335-48:
(8*8)+(7*6)+(6*9)+(5*3)+(4*3)+(3*5)+(2*4)+(1*8)=218
218 % 10 = 8
So 869335-48-8 is a valid CAS Registry Number.

869335-48-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-methylpyrrolo[2,3-b]pyridin-4-amine

1.2 Other means of identification

Product number -
Other names 1-methyl-1H-pyrrolo[2,3-b]pyridine-4-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:869335-48-8 SDS

869335-48-8Relevant academic research and scientific papers

Novel Azole fused pyridinyl urea derivatives or pharmaceutically acceptable salts thereof, preparation method therof and pharmaceutical composition for use in preventing or treating Urotensin-Ⅱ receptor activity related diseases containing the same as an active ingredient

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, (2021/05/22)

The present invention refers to novel azole-junction pyridyl urea derivatives or a pharmaceutically acceptable salt, including effect because of having immunosuppressive effect and manufacturing method thereof urotensin-II receptor activity associated for preventing or treating disease is directed to pharmaceutical composition. Azole the present invention according to a urea derivatives pyridyl-junction U-II receptor antagonist to may be based on congestive heart failure, heart ischemia, myocardial infarction, heart hyperplasia, cardiac fibrosis, coronary artery disease, arteriosclerosis, hypertension, asthma, renal failure, diabetes, vascular inflammatory, neurodegenerative diseases, stroke, pain, depression, such as psychotic and cancer-associated diseases, receptor activity U-II preventing or useful in the treatment of a, use can be made of,.

Substituted Phenylamino-Pyrimidines

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, (2008/12/04)

The invention relates to substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.

SUBSTITUTED PHENYLAMINO-PYRIMIDINES

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Page/Page column 52, (2010/02/14)

The invention relates to substituted phenylamino-pyrimidines, to a method for their production and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular for the treatment of cardiovascular diseases.

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