869368-49-0

Basic information

• Product Name: (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]valinyl]amino]-5-(t-butyloxycarbonylamino)-1,6-diphenyl-3-hydroxyhexane
• Synonyms: (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]valinyl]amino]-5-(t-butyloxycarbonylamino)-1,6-diphenyl-3-hydroxyhexane
• CAS NO: 869368-49-0
• Molecular Weight: 679.924
• Mol File: 869368-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]valinyl]amino]-5-(t-butyloxycarbonylamino)-1,6-diphenyl-3-hydroxyhexane(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]valinyl]amino]-5-(t-butyloxycarbonylamino)-1,6-diphenyl-3-hydroxyhexane(869368-49-0)
• EPA Substance Registry System: (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]valinyl]amino]-5-(t-butyloxycarbonylamino)-1,6-diphenyl-3-hydroxyhexane(869368-49-0)

Safety Data

• Hazardous Substances Data: 869368-49-0(Hazardous Substances Data)

Upstream product

• 224631-15-6 N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]-L-valinyl hydroxysuccinimide ester 
• 144163-85-9 (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane 
• 154212-61-0 N-((N-Methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)-carbonyl)-L-valine 

Downstream Products

• 869368-50-3 (2S,3S,5S)-2-[N-[N-[[N-methyl-N-[(2-isopropyl-4-thiazolyl)methyl]amino]carbonyl]vanilyl]amino]-5-amino-1,6-diphenyl-3-hydroxyhexane 

Relevant articles and documents

RITONAVIR ANALOGOUS COMPOUND USEFUL AS RETROVIRAL PROTEASE INHIBITOR, PREPARATION OF THE RITONAVIR ANALOGOUS COMPOUND AND PHARMACEUTICAL COMPOSITION FOR THE RITONAVIR ANALOGOUS COMPOUND.

The present invention describes a new one ritonavir analogous compound that presents significantly superior activity in inhibition of HIV protease. There are also described the usage of the ritonavir analogous compound of the present invention or salt, ester or prodrug thereof as well as the usage of the compound and its pharmaceutical compositions in medicine, particularly, in the treatment of HIV infection, by itself or in combination with others anti-HIV drugs.