869376-48-7Relevant academic research and scientific papers
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors
Brizzi, Antonella,Cascio, Maria Grazia,Brizzi, Vittorio,Bisogno, Tiziana,Dinatolo, Maria Teresa,Martinelli, Adriano,Tuccinardi, Tiziano,Di Marzo, Vincenzo
, p. 5406 - 5416 (2008/03/18)
In our ongoing program aimed at the design, synthesis, and biological evaluation of novel cannabinoid receptor ligands derived from olivetol and hexyl-resorcinol, we have designed a structural model for new derivatives on the basis of a previous study. He
Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors
Brizzi, Antonella,Brizzi, Vittorio,Cascio, Maria Grazia,Bisogno, Tiziana,Sirianni, Rossella,Marzo, Vincenzo Di
, p. 7343 - 7350 (2007/10/03)
Despite their different chemical structures, Δ9- tetrahydrocannabinol (THC) and anandamide (AEA) have common pharmacological properties. This study was aimed at finding new cannabinoid receptor ligands that overcome the instability of AEA and i
