86938-81-0

Basic information

• Product Name: 1-[2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinolin-3-yl]-ethanone
• CAS NO: 86938-81-0
• Molecular Weight: 316.359
• Mol File: 86938-81-0.mol

Chemical Properties

• CAS DataBase Reference: 1-[2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinolin-3-yl]-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinolin-3-yl]-ethanone(86938-81-0)
• EPA Substance Registry System: 1-[2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinolin-3-yl]-ethanone(86938-81-0)

Safety Data

• Hazardous Substances Data: 86938-81-0(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 61001-01-2 2-(4-methoxyphenyl)imidazo[2,1-a]isoquinoline 

Relevant articles and documents

RESEARCH ON IMIDAZOISOQUINOLINE DERIVATIVES. 3. ACYLATION OF 2-SUBSTITUTED IMIDAZOISOQUINOLINES

The acylation of 2-alkyl, 2-aryl, and 2-hetaryl derivatives of imidazoisoquinoline was studied. 3-Acetyl-substituted derivatives of this system were synthesized by the action of acetic anhydride on 2-arylimidazoisoquinolines in the presence of magnesium perchlorate.Under similar conditions 2-hetaryl derivatives are acetylated not only in the 3 position but also in the hetaryl ring. 3-Acetyl-2-methylimidazoisoquinoline, which is not formed as a result of direct acylation, was synthesized by indirect methods, viz., on the basis of 1-aminoisoquinoline and 3-chloroacetylacetone or from 1-acetamidoisoquinoline and bromoacetone.The compounds obtained are extremely resistant to hydrolysis, give the usual reactions at the carbonyl group, condense with aromatic aldehydes, and undergo bromination to give 3-bromo- and 3-dibromoacetyl derivatives.