869383-25-5Relevant articles and documents
Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents
Hocke, Carsten,Prante, Olaf,L?ber, Stefan,Hübner, Harald,Gmeiner, Peter,Kuwert, Torsten
, p. 4819 - 4823 (2005)
A series of fluoro substituted aryl carboxamides was synthesized revealing high affinity for the dopamine D3 receptor. In contrast to 2-methoxy substitution, a 2,3-dichloro substitution pattern at the phenylpiperazine moiety induces a 10-fold increase of