869489-01-0

Basic information

• Product Name: 4-[(3S,5S)-1-tert-butoxycarbonyl-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazine-1-carboxylic acid benzyl ester
• Synonyms: 4-[(3S,5S)-1-tert-butoxycarbonyl-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazine-1-carboxylic acid benzyl ester
• CAS NO: 869489-01-0
• Molecular Weight: 522.592
• Mol File: 869489-01-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(3S,5S)-1-tert-butoxycarbonyl-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3S,5S)-1-tert-butoxycarbonyl-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazine-1-carboxylic acid benzyl ester(869489-01-0)
• EPA Substance Registry System: 4-[(3S,5S)-1-tert-butoxycarbonyl-5-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-3-yl]piperazine-1-carboxylic acid benzyl ester(869489-01-0)

Safety Data

• Hazardous Substances Data: 869489-01-0(Hazardous Substances Data)

Upstream product

• 869488-91-5 (S)-2-(3,3-difluoropyrrolidine-1-carbonyl)-4-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 31166-44-6 phenylmethyl 1-piperazinecarboxylate 

Downstream Products

• 869489-00-9 (2S,4S)-2-(3,3-difluoropyrrolidine-1-carbonyl)-4-piperazin-1-ylpyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Therapeutic compounds

The invention provides compounds of formula (I), prodrugs and stereoisomers thereof, and the pharmaceutically acceptable salts of the compounds, prodrugs, and stereoisomers, wherein R1, R2, R3, HET, n, Q, X, Y, and Z are as described herein; compositions thereof; and uses thereof in treating diabetic complications including diabetic neuropathy, diabetic nephropathy, diabetic microangiopathy, and the like.