869497-75-6 Usage
Uses
A highly selective histamine H4 receptor silent antagonist
Biological Activity
Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .
Check Digit Verification of cas no
The CAS Registry Mumber 869497-75-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,4,9 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 869497-75:
(8*8)+(7*6)+(6*9)+(5*4)+(4*9)+(3*7)+(2*7)+(1*5)=256
256 % 10 = 6
So 869497-75-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H15ClN4O.C4H4O4/c1-17-4-6-18(7-5-17)13(19)12-15-10-3-2-9(14)8-11(10)16-12;5-3(6)1-2-4(7)8/h2-3,8H,4-7H2,1H3,(H,15,16);1-2H,(H,5,6)(H,7,8)/b;2-1-
