869541-33-3

Upstream product

• 869541-31-1 2-benzyl-1,3,3-trioxo-1,2-dihydronaphtho[1,2-d]isothiazole-4-carboxylic acid benzyl ester 
• 869541-14-0 1,3,3-trioxo-1,2-dihydronaphtho[1,2-d]isothiazole-4-carboxylic acid 
• 869541-13-9 2-tert-butylsulfamoylnaphthalene-1,3-dicarboxylic acid 

Downstream Products

• 869541-35-5 2-benzyl-1,3,3-trioxo-1,2-dihydronaphtho[1,2-d]isothiazole-4-carboxylic acid ethoxycarbonylmethyl ester 

Relevant academic research and scientific papers

Naphtho[1,2-d]isothiazole acetic acid derivatives as a novel class of selective aldose reductase inhibitors

Acetic acid derivatives of naphtho[1,2-d]isothiazole (NiT) were synthesized and tested as novel aldose reductase (ALR2) inhibitors. The parent compound 11 exhibited a fair inhibitory activity (IC50 = 10 μM), which was enhanced by 2 orders of ma