869582-17-2Relevant academic research and scientific papers
Inhibition of secretory phospholipase A2. 1-Design, synthesis and structure-activity relationship studies starting from 4- tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA 2s
Assogba, Leon,Ahamada-Himidi, Azali,Habich, Nadia Meddad-Bel,Aoun, Darina,Boukli, Latifa,Massicot, France,Mounier, Carine M.,Huet, Jack,Lamouri, Aazdine,Ombetta, Jean-Edouard,Godfroid, Jean-Jacques,Dong, Chang-Zhi,Heymans, Franoise
, p. 850 - 861 (2007/10/03)
Starting from 4-tetradecyloxybenzamidine (PMS815), a non-specific inhibitor of GI and GII PLA2s, we report in this work the discovery of the specificity through design, synthesis and structure-activity relationships studies of different kinds o
