869586-85-6

Upstream product

• 53250-83-2 2-chloro-4-(methanesulfonyl)benzoic acid 

Downstream Products

• 869586-86-7 2-chloro-4-methanesulfonylbenzonitrile 
• 106738-52-7 2-chloro-4-methanesulfonyl-benzylamine; hydrochloride 
• 869587-12-2 (3S)-1-[(2S)-2-[(tert-butoxycarbonyl)amino]-3-[3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-oxohex-5-en-1-yl]-3-fluoropyrrolidine 
• 869587-11-1 C₂₃H₃₀ClN₅O₇S 
• 869587-10-0 C₁₈H₂₂ClN₃O₇S 
• 869587-09-7 C₁₉H₂₄ClN₃O₇S 
• 869586-87-8 2-chloro-4-methylsulphonyl-N'-hydroxybenzenecarboximidamide 

Relevant academic research and scientific papers

Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase

A series of potent nicotinamide inhibitors of soluble epoxides hydrolase (sEH) is disclosed. This series was designed using structure-based deconstruction and a combination of two HTS hit series, resulting in hybrid analogs that retained the optimal poten

SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME

Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.

SUBSTITUTED PYRIDINEAMIDE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS

Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.

1,2,4-OXADIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel 1,2,4-oxadiazole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.