869591-74-2Relevant academic research and scientific papers
HIV INTEGRASE INHIBITORS: CYCLIC PYRIMIDINONE COMPOUNDS
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Page/Page column 62, (2010/11/27)
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed. Formula: (I).
HIV integrase inhibitors: cyclic pyrimidinone compounds
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Page/Page column 21, (2008/06/13)
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed.
