869683-45-4Relevant academic research and scientific papers
A simplified synthesis of (R)-(-)-muscone using a ring-opening reaction of (R)-(+)-β-methyl-β-propiolactone
Morita, Motoaki,Mase, Nobuyuki,Yoda, Hidemi,Takabe, Kunihiko
, p. 3176 - 3182 (2005)
A chiral macrocyclic precursor can be constructed via a ring-opening reaction of (R)-(+)-β-methyl-β-propiolactone with a functionalized organocuprate with no loss of enantiomeric excess. The carboxylic acid precursor was used as a chiral building block for the synthesis of chiral muscone and musky macrolactones.
