869715-02-6

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 110850-30-1 benzyl-2,3-dihydroxy- 4,6-O-benzylidene-β-D-galactopyranoside 
• 108-24-7 acetic anhydride 
• 10343-13-2 benzyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 869715-06-0 benzyl [3,4,6-tri-O-acetyl-2-deoxy-2-(2',2',2'-trichloroethoxycarbonyl-amino)-β-D-galactopyranosyl]-(1->4)-2,3-di-O-acetyl-6-O-benzyl-β-D-galactopyranoside 
• 156632-82-5 benzyl (3,4,6-tri-O-acetyl-2-deoxy-2-acetamido-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-galactopyranoside 
• 869715-04-8 benzyl 2,3-di-O-acetyl-6-O-benzyl-β-D-galactopyranoside 

Relevant academic research and scientific papers

A facile synthesis of the GalNAcβ1→4Gal target sequence of respiratory pathogens

The carbohydrate sequence, GalNAcβ1→4Gal, is the target for the adhesion of several respiratory pathogens. The sequence was prepared in an optimized synthesis in forms that allow conjugation to scaffolds or surfaces.

SYNTHESIS AND (13)C-N.M.R. SPECTROSCOPY OF 2-O- AND 6-O-ACETYL-3-O-α-L-RHAMNOPYRANOSYL-D-GALACTOSE, CONSTITUENTS OF BACTERIAL CELL-WALL POLYSACCHARIDES

Benzyl 2-O-acetyl-4,6-O-benzylidene-3-O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-β-D-galactopyranoside (11) has been synthesised by two routes.Partial deacetylation of 11 and then acid hydrolysis yielded benzyl 2-O-acetyl-3-O-α-L-rhamnopyranosyl-β-D-galactopyranoside, catalytic hydrogenolysis of which gave the first title compound in excellent yield.Benzyl 4,6-O-benzylidene-3-O-α-L-rhamnopyranosyl-β-D-galactopyranoside was benzylated, and hydrogenolysis (LiAlH4-AlCl3) of the product gave the disaccharide derivative 16 with only HO-6 unsubstituted.Acetylation of 16 followed by catalytic hydrogenolysis gave the crystalline, second title compound.As model compounds for comparative n.m.r. studies, 2-O-, 3-O-, and 6-O-acetyl-D-galactose were also synthesised.