869720-31-0Relevant academic research and scientific papers
Tandem Zn-Brook rearrangement/ene-allene carbocyclization
Unger, Rozalia,Cohen, Theodore,Marek, Ilan
, p. 1749 - 1756 (2009)
The addition of metalated alkynes to acylsilanes leads to the corresponding α-propargylsilanol derivatives. On addition of ZnBr2, Zn-promoted Brook rearrangements take place to produce the propargyl/allenylzinc bromides, which undergo cyclization to give functionalized carbocycles as single diastereoisomers. Wiley-VCH Verlag GmbH & Co. KGaA.
