86980-86-1

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 6380-23-0 3,4-dimethoxystyrene 
• 86980-84-9 2-(3,4-Dimethoxyphenyl)-2,3,3a,4,5,6-hexahydropyrrolo<1,2-b>isoxazole 

Relevant academic research and scientific papers

General Synthesis of Phenanthroindolizidine, Phenanthroquinolizidine, and Related Alkaloids: Preparation of (+/-)-Tylophorine, (+/-)-Cryptopleurine, (+/-)-Septicine, and (+/-)-Julandine

A general synthetic route to the pentacyclic phenanthro class and related indolizidine and quinolizidine alkaloids via β-amino ketone intermediates is reported.The synthesis of tylophorine, cryptopleurine, septicine, and julandine, in racemic forms, has been described.Synthetic steps in the preparation of these alkaloids involve 1,3-dipolar cycloadditions of the cyclic nitrones as a common feature followed by crucial ring closure by aldol reactions and photolyses.