86983-58-6

Upstream product

• 86983-43-9 1-(m-chlorophenyl)-3-methyl-3-phenylbutan-1-ol 
• 515-40-2 neophyl chloride 
• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 32597-92-5 (3-chlorobenzyl)triphenylphosphonium chloride 
• 826-55-1 2-methyl-2-phenylpropionic acid 
• 2173-69-5 2-methyl-2-phenyl-propan-1-ol 
• 587-04-2 m-Chlorobenzaldehyde 

Relevant academic research and scientific papers

Br?nsted Acid-Catalyzed Intramolecular Hydroarylation of β-Benzylstyrenes

Using triphenylmethylium tetrakis(pentafluorophenyl)borate as a convenient Br?nsted acid precatalyst, β-(α,α-dimethylbenzyl)styrenes are shown to cyclize efficiently to afford a variety of new indanes that possess a benzylic quaternary center. The geminal dimethyl-containing quaternary center is proposed to be necessary to arm the substrate for cyclization through steric biasing.

The Preparation and Photolysis of (E)-1-Aryl-3-methyl-3-phenylbut-1-enes

Reaction of 2-methyl-2-phenylpropylmagnesium chloride with benzaldehyde in tetrahydrofuran gave, 2,7-dimethyl-2,4,5,7-tetraphenyloctane-4,5-diol as a 1:2 mixture of clear transparent crystalline plates (meso) and needles (+/-), 3-methyl-1,3-diphenylbutan-1-one, benzyl alcohol, 2-methyl-2-phenyl-propane and a low yield of 3-methyl-1,3-diphenylbutan-1-ol.The distinction between the meso- and the (+/-)-diols was unequivocal because the unique space group of the former requires the dimeric molecules to lie about a crystallographic centre of symmetry.The mechanism involved in the formation of the products of the Grignard reaction is examined.By careful choice of reaction conditions a series of 1-aryl-3-methyl-3-phenylbutan-1-ols were prepared.Dehydration of the 1-aryl-3-methyl-3-phenylbutan-1-ols with p-toluenesulfonic acid and a short reaction time gives (E)-1-aryl-3-methyl-3-phenylbut-1-enes but longer reaction times afford 3-aryl-1,1-dimethylindanes.Photolysis of the (E)-1-aryl-3-methyl-3-phenylbut-1-enes affords (Z)-1-aryl-3-methyl-3-phenylbut-1-enes and trans-1-aryl- 3,3-dimethyl-2-phenylcyclopropanes.Extended photolysis gives 4-aryl-2-methyl-3-phenylbut-1-enes via trans-1-aryl-3,3-dimethyl-2-phenylcyclopropane by rupture of the cyclopropyl bond adjacent to the aryl substituent.